The Sec-dependent pathway
نویسندگان
چکیده
منابع مشابه
Secretion of the chlamydial virulence factor CPAF requires the Sec-dependent pathway
The chlamydial protease/proteasome-like activity factor (CPAF) is secreted into the host cytosol to degrade various host factors that benefit chlamydial intracellular survival. Although the full-length CPAF is predicted to contain a putative signal peptide at its N terminus, the secretion pathway of CPAF is still unknown. Here, we have provided experimental evidence that the N-terminal sequence...
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Significant strides have been made during the past 20 years in our understanding of protein secretion across the bacterial inner membrane. Specialized chaperones select secretory polypeptide chains and usher them to a membrane-embedded preprotein translocase. This unique molecular machine envelops the polymeric substrate and migrates along its length in defined, energy-dependent steps. Conseque...
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As obligate intracellular, vector-borne bacteria, rickettsiae must adapt to both mammalian and arthropod host cell environments. Deciphering the molecular mechanisms of the interactions between rickettsiae and their host cells has largely been hindered by the genetic intractability of these organisms; however, research in other gram-negative pathogens has demonstrated that many bacterial determ...
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Introduction : The aim of this study is to obtain new insight into possible relation between functional properties of slow concealed pathway and rate-dependent properties of AV-node. Methods : Rate-dependent nodal properties of recovery, facilitation, and fatigue were characterized by stimulation protocols in one groups of (N=7) isolated superfused AV-Nodal rabbits. Small miniature lesions ...
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Citrus Huanglongbing (HLB) is the most destructive citrus disease worldwide. HLB is associated with three species of the phloem-limited, gram-negative, fastidious α-proteobacteria: Candidatus Liberibacter asiaticus (Las), Ca. L. americanus (Lam), and Ca. L. africanus (Laf) with Las being the most widespread species. Las has not been cultured in artificial media, which has greatly hampered our e...
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ژورنال
عنوان ژورنال: Research in Microbiology
سال: 2013
ISSN: 0923-2508
DOI: 10.1016/j.resmic.2013.03.007